I'm amazed how quickly spambots find a new site. Especially the comment spammers. When I had this on a temp URL, it had been found within two weeks. My solution? Turn off anonymous commenting. Easy, because it didn't matter, and there were no users to speak of.
But six hours after I pushed this site public, the comment spammers were at it again. Formerly, the site was running on wordpress. There, I used spam karma 2 to stem the tide: it worked really well.